Discussion on the ageing of skin questions

Discussion on the ageing of skin questions
Which of the following statements
is true regarding classical HutchinsonGilford progeria syndrome (HGPS)?
A. cancer risk is high, including thyroid
neoplasms, melanoma, meningioma,
soft tissue sarcomas, hematologic/
lymphoid cancers and osteosarcomas
B. causative gene is WRN
C. inheritance is autosomal dominant
D. main symptoms include a lack of the
pubertal growth spurt during early
teen years, greying or loss of hair,
scleroderma-like skin lesions and
characteristic facies
E. onset of symptoms is usually second
to third decade of life (adulthood progeria)
Question 46
Which of the following statements
concerning the ageing of skin is true?
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